2 4 Dinitrophenol is manufactured compound, that do not occur naturally. Originating from phenol substances it contains two nitro groups. Soluble in alkaline, sodium salts and ammonium. Also soluble in chloroform, acetone and alcohols. DNP decreases ATP production and increases energy consumption by mitochondria. Acting as proton ionophore in living cells it uncouples oxidative phosphorylation by transporting protons through the membrane. Leading to increased oxygen consumption and low formation of adenosine triphosphate.
Use of 2 4 Dinitrophenol
2 4 DNP was found in early 20th century and was used for wood preservation, dynamite detonation and as a dye. When factory workers, working with dinitrophenol began to complain about rapid weight loss it is come to public attention that DNP has incredible fat loss capabilities. It then was largely used as dieting aid by over 100 000 peoples up until 1938, when FDA prohibited administration of 2 4 DNP for human consumption. Now it only used as herbicide, defoliant and desiccant. Dinitrophenol is still remains very popular among bodybuilders as underground weight loss supplement.
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|Signal Word||Danger||GHS-Symbol||skull and crossbones health hazard environmental hazards|